The clinical evidence is clear on this point, and no amount of anecdotal reports changes the trial data
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Lactobacillus strains, in particular, can lower the pH of urine, creating an environment thats less favorable for harmful bacteria
Healthcare providers should assess for: Persistent gastrointestinal symptoms that may indicate gallbladder disease Signs of pancreatitis (severe abdominal pain radiating to the back) Changes in vision or symptoms of diabetic retinopathy progression, especially in patients with pre-existing retinopathy Signs of dehydration or acute kidney injury with severe gastrointestinal symptoms Hypoglycemia when used with insulin or sulfonylureas (which may require dose reduction of these medications) Symptoms related to the boxed warning (thyroid tumors): neck mass, hoarseness, dysphagia, or dyspnea Patients should be aware that semaglutide is contraindicated during pregnancy and lactation, and women of childbearing potential should stop treatment approximately 2 months before a planned pregnancy

However, since semaglutide can influence the hormonal environment and potentially reach maternal and fetal tissues via the placenta, most healthcare professionals advise pregnant women or those planning pregnancy to avoid GLP-1 receptor agonists like Ozempic