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Consistent with these findings, experimental models demonstrate that T3 supplementation alleviates liver fibrosis by restoring mitochondrial biogenesis, enhancing -oxidation of fatty acids, and normalizing autophagic flux
(2014) 9:e101223
At the methodological level, isotope tracing technologies can directly resolve actual metabolic flux changes, single-cell and spatial multi-omics can help identify cell-cell interactions and substrate competition in the tissue microenvironment, and genome-scale metabolic modeling can be used for priority ranking and assessment of targetability
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J Int Soc Sports Nutr 10(1):6 [DOI] [PMC free article] [PubMed] [Google Scholar] 53.Li N, Chen S, He Y, Chen Y, Duan X, He W et al (2025) Effects of oral supplementation of beta -hydroxy-beta -methylbutyrate on muscle mass and strength in individuals over the age of 50: a meta-analysis
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