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Human research dosing is typically in the range of 250500 mcg daily, administered subcutaneously or orally (noting that oral bioavailability data in humans is limited)

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[14] [15] Both agents can influence insulin sensitivity and cardiovascular risk markers, and their combined effects on lipid profiles and blood pressure are not yet fully characterised

Splitting the dose may provide more consistent receptor engagement throughout the day compared to taking both tablets at once

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