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IV zinc differs in several ways: Delivered directly into circulation Avoids gastrointestinal irritation Allows for predictable absorption Can be combined with hydration and other supportive nutrients IV administration may be considered when oral intake is insufficient, poorly tolerated, or ineffective in meeting short-term physiological demand

Other studies implicate a loss of GABAergic interneurons in aging rat models of MCI, suggesting that multiple mechanisms may play a role and/or may interact to contribute to hyperactivity (273, 274)

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About a fifth of cases of dementia are related to strokes or insufficient blood flow to the brain, these cases being known as vascular dementia