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Effect of mecobalamin on diabetic neuropathies: Beijing Methycobal Clinical Trial Collaborative Group

Vegetarians and vegans: As B12 is primarily found in animal products, strict plant-based diets can increase the risk of deficiency

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B12 injections deliver the vitamin directly into the bloodstream, ensuring maximum absorption and immediate effects, whereas oral supplements must pass through the digestive system, which can result in lower absorption rates and slower onset of action

These patients are often recommended to receive 1 mg of oral vitamin B12 daily indefinitely, but intramuscular injections may be necessary if oral supplementation is insufficient Mahawar2018Langan2017