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A., Hsiao, J

[ 3 ] Interestingly, one study that measured circulating DSIP levels in humans found that levels were actually lowest at night and highest in the afternoon, which was the opposite of what would be expected for a straightforward sleep-promoting factor

rather, it provides one possible framework in which such effects may be embedded within a broader multi-level process that could, in some individuals or contexts, be shaped more strongly by central valuation and motivational mechanisms (Figure 2)