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Circulation 116:15851595 Soriano FG, Virag L, Szabo C (2001) Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly- (ADP-ribose) polymerase activation

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Moreover, in flavoproteinopathies such as AIFM1 or FLAD1 mutations, depletion of FAD leads to misfolding and functional loss of affected proteins