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UV Radiation Sun exposure stimulates melanocytes, the cells responsible for melanin production

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Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes

This potent antioxidant is naturally produced in the body and can also be found in many foods, including fruits, vegetables, and meats

Genes linked to vitiligo pathogenesis are categorized into five groups: transcription factors/co-regulators, adaptive immunity, innate immunity, cellular signaling/adaptor proteins/receptors, and nonimmune genes (Jin et al., 2016