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Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency

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V.SimonsK

The antioxidant role of GSH GSH is implicated in several functions, including antioxidant defense with reduction of oxidative stress and maintenance of redox balance, metabolic detoxification from xenobiotics and exogenous compounds, cell cycle regulation, and immune system modulation, as well as fibrogenesis ( Its main role is to shield cellular macromolecules from endogenous and exogenous reactive oxygen species (ROS) and nitrogen ones

We found that AA-exposed mice exhibited significantly greater airway hyperreactivity compared to PBS and melatonin-only controls ( Figure 1O ), alongside reduced dynamic compliance ( Figure 1P )