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The Journal of Investigative Dermatology

Nat Commun, 2025

[10] [11] It's important to understand that GLP-1 medications are initiated at a low dose and gradually increased over several weeks to minimise gastrointestinal side effects such as nausea and vomiting

Avoid areas too close to the joints to prevent hitting muscles

No direct contraindication exists between ashwagandha and tirzepatide, but limited clinical evidence means you should obtain explicit approval from your healthcare provider before combining them