Duration of treatment : Longer treatment periods may allow for better establishment of behavioral changes, though this doesn't prevent biological drivers of weight regain
Finally, we discuss whether the inhibition of tryptophan hydroxylase (TPH), in particular the neuronal isoform (TPH2), may provide an opportunity to pharmacologically target central 5-HT synthesis, and so develop new treatments for severe, life-threatening SS
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The initial excitement of rapid loss fades
Research published in the New England Journal of Medicine has shown that tirzepatide produces greater average weight loss than semaglutide in patients with obesity, which means some patients do eventually want to explore both medications over the course of their treatment