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This ultimately results in loss of feedback inhibition and increased production of 5-oxoproline from its precursor gamma glutamylcysteine

Skulachev for discussion of problems regarded in this paper

2.9 Single-cell transcriptomic analysis To investigate the expression patterns of key genes across different cell types and their dynamic changes within the RA immune microenvironment, the GSE159117 dataset was downloaded from the GEO database and subjected to systematic single-cell transcriptomic analysis