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Pathophysiological mechanisms of HE HE occurs due to a combination of distinct pathophysiological mechanisms such as inflammation [32], oxidative stress [33], impaired bloodbrain barrier (BBB) permeability, neurotoxins, impaired energy metabolism of the brain [34] and more (Fig

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Proper refrigerated storage: Store in main refrigerator section (not freezer) Keep away from freezer compartment (avoid freezing) Don't store in door (temperature fluctuates) Protect from light (keep in box or wrap in foil) Label with reconstitution date Signs of degradation: Cloudiness or particles (should be clear) Color change (should remain same color as when mixed) Unusual odor Loss of effectiveness If you notice any of these, discard and prepare fresh solution

Vincent, P.A

Store per the label