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Click to read the study in NEJM Relevant Reading: Heart Failure with Preserved Ejection Fraction A Metabolic Disease

First, BPC 157 therapy induces the healing of corneal ulcers [76]

However, this aspect of its action is potentially problematic in PWS, since many individuals with PWS already have decreased stomach emptying rates and generally slow GI transit (which does not seem to reduce their appetite)

Both Ozempic and Wegovy are formulated to aid in weight management and improve pancreatic function by increasing insulin production

As a consequence, the true HR would potentially be more in favor of GLP-1 RAs than the HRs observed in this study