Singla, West China Hospital, Sichuan University, China Reviewed by Huazhen Xu, Johns Hopkins Medicine, United States Yu Chiang Hung, Kaohsiung Chang Gung Memorial Hospital, Taiwan Updates Copyright 2024 Tang, Zhuang, Zhao, Gu, Zhang, Bi, Wang, Bao, Li, Zhang and Zhu
However, the clinical application of these approaches is still in its early stages, and significant gaps remain in our understanding of their feasibility, risks, and challenges
These modifications are discussed in research literature for their effect on reducing binding affinity to insulin-like growth factor binding proteins, resulting in extended biological half-life in experimental models
39 GuoJ.XuB.HanQ.ZhouH.XiaY.GongC.et al (2018)
Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6