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Individuals also tend to lose about of a quarter of their weight in lean muscle mass due to reduced food intake from gastrointestinal distress, lack of appetite, or a combination of the two

View image online ( woman holding GLP1 injection pen Women of reproductive age are increasingly prescribed GLP-1 drugs for weight-management support, but the risks and benefits of using these medications before pregnancy is still poorly understood

Figure 1 Table 1 Effects of GIP receptor agonism or antagonism on glycemic control, body weight, and energy balance in animal models of obesity and diabetes (modified according to Campbell and Nauck) (47, 49)