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In response to vascular injury or stimulation by cytokines and growth factors, VSMCs can transition from a contractile to a synthetic phenotype

Stress management and adequate sleep can also support a more stable gut environment

Normally, these cytokines are used to trigger an inflammatory response against infection (such as a fever)

Glutathione does reduce oxidative stress markers (MDA, 4-HNE) during acute alcohol exposure, which theoretically lowers hepatocyte damage

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