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But these results have already had an immediate impact

Food and Drug Administration (FDA) in 2021 for chronic weight management in adults and children 12 and older with obesity (BMI of 30 or more) and for adults who are overweight (BMI of 27 or more) with one or more weight-related health conditions, such as type 2 diabetes or high blood pressure

Following ligand binding, activation of the Epac/PI3K/Akt signaling axis promotes mitochondrial biogenesis, enhances insulin sensitivity, and suppresses apoptotic signaling, thereby supporting cellular energy homeostasis

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