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In a large study of over 18,000 patients, rates of gastrointestinal side effects were similar between tirzepatide and semaglutide users, with no significant difference between the drugs

California Department of Health Care Services spokesperson Tessa Outhyse said in an email that the official advice to try those other approaches now is not meant to dismiss any past efforts, but to encourage Medi-Cal members to take a renewed, proactive, and medically supported approach with their healthcare provider that may appropriately include these additional options. But that may be unrealistic, said Kurt Hong, founding director of the Center for Clinical Nutrition at Keck School of Medicine of USC

Understanding the safety, efficacy, and monitoring requirements of these medications in fatty liver disease is essential for informed treatment decisions

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