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Ethics statement The animal study was approved by Guilin Medical University Institutional Animal Care and Use Committee

In a hamster model of fibrosis bleomycin induced, A1AT demonstrated to reduce neutrophil and lymphocyte migration already after 7 days, with a further decrease in cell counts (neutrophils, lymphocytes, and macrophages) after 30 days (71)

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There is a medically approved treatment for raising glutathione levels that is primarily used to counteract Tylenol toxicity

According to NICE guidance, GLP-1 receptor agonists are recommended for specific patient groups with type 2 diabetes (NG28) and, in some formulations like Wegovy (semaglutide 2.4mg) and Saxenda (liraglutide 3mg), for weight management in adults with obesity or overweight with weight-related comorbidities