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Conclusions Despite the small sample size groups in many studies, the randomized clinical trials showed positive hyperbaric oxygen therapy results in reducing the oxidative markers in fibromyalgia

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In one trial, 16 people placed on experimental bed rest for 3 weeks (in order to increase urinary calcium excretion by causing bone breakdown) and treated with 20 mg per day of the bisphosphonate alendronate had lower urine calcium concentrations, and lower calcium oxalate and calcium phosphate saturations, compared with placebo (Ruml 1995)

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