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A major milestone occurred in 2015, when Kybella and Belkyra were the first officially approved fat-dissolving injectables (strictly approved for the treatment of submental fat, i.e., double chin), giving medical legitimacy to the concept

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Inhibition of IDH1 also sensitized CCNE1-driven tumours to olaparib in vivo (Fig

The PDHA1 gene is located on chromosome Xp22.12 and is composed of 12 exons that generate four alternatively spliced mRNAs, each of which encodes a distinct protein isoform

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