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In addition to direct bone marrow suppression, mycophenolate is also associated with gastrointestinal bleeding, and resultant anemia from blood loss

Anderson et al., 1987

DMF/MMF actions may also be indirect, including blocking of cytokine-activated I-B, a cytoplasmic complex that can induce degradation of a NF-B inhibitor, releasing inflammatory transcription factors to the nucleus to induce inflammation

Im more proactive when a raised GGT sits alongside central weight gain, poor fasting markers, high blood pressure, or a history that fits fatty liver risk

Taken together, -glucan can prevent or reverse immune tolerance by altering the relevant metabolic and epigenetic pathways and TI induction