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Summary: GLP-1/GIP medications help reduce inflammation in metabolic organsnot autoimmune or pain-related inflammation They DO: lower CRP and related metabolic inflammatory/oxidative stress biomarkers, improve metabolic liver disease activity in steatohepatitis settings, improve cardiometabolic risk markers such as blood pressure improve kidney outcomes in high-risk CKD populations (semaglutide

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Glutathione s-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing

Publicly available datasets reported in this paper are from the GEO databases (GSE13911, GSE27342, and GSE13861) and The Cancer Genome Atlas

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