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Signaling Pathways Affected by L-Carnitine Extensive research has focused on elucidating the signaling pathways associated with L-Carnitine, highlighting the involvement of Sirtuin 3 (SIRT3) [72] and nuclear factor erythroid 2-related factor 2 (Nrf2) [73]

Ethics declarations Ethics approval and consent to participate Animal studies and procedures were carried out in accordance with an approved protocol from the Institutional Animal Care and Use Committee (IACUC) at the Fourth Military Medical University (IACUC-20220505)

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 2% by weight of the cholesterol

Glutathione treatment decreased ALT levels in ALT responders (Fig

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