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It stimulates a robust GH pulse without significantly altering cortisol, prolactin, or appetite hormones, making it a highly predictable and tolerable option for long-term patient use

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However, more patients on exenatide had adverse events, predominantly gastrointestinal effects such as nausea and diarrhea, and discontinued therapy

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These patients who do not fit the criteria but who remain undiagnosed B12 deficient patients become very expensive for the NHS to look after