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In addition, organic cation transporters OCT-1 (encoded by SLC22A1 ) and OCT-2 (encoded by SLC22A2 ) expressed in renal proximal tubules are responsible for excretion of organic cations and most exogenous drugs
S.DeaneJ.SchwabK.CheongA.RosamiliaA.et al (2014)
In summary, System X c /GSH/GPX4 axis-based ferroptosis may be a research direction for reversing drug resistance and may provide a rational basis for the development of new therapies for drug resistant solid tumors
Kwon, D.R., & Park, G.Y
It accesses doses lower than our usual starter doses as well as additional doses up to 25% of the standard maintenance dose
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