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Amyloid PET and tau PET not only reflect the overall accumulation and spatial distribution of amyloid plaques and NFTs but may also detect abnormal brain changes earlier than neurodegeneration, thus providing opportunities for early intervention in the disease

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It has also been suggested that the combination of folate, vitamin B12, and vitamin B6 may improve methylation, increase transsulfuration, and possibly reduce stress

doi: 10.1210/en.2008-1733 117 RoaJAguilarEDieguezCPinillaLTena-SempereM