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A 2018 meta-analysis of 14 studies with over 1,000 participants found that chitosan, when paired with a calorie-restricted diet and exercise, led to a modest weight loss of about 1 kg over several weeks compared to a placebo group, which actually gained 1.5 kg in some cases

Although this was demonstrated in animal experiments, GLP-1 was shown to exert acute anti-inflammatory and antioxidant effects on humans under specific conditions

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