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A recent network meta-analysis of RCT comparing incretin-based drugs for the management of obesity in non-diabetic subjects supported the superiority of tirzepatide in achieving a greater percentage of BW loss compared to semaglutide 2.4 mg and liraglutide 3.0 mg (5.13%, 95% CI 9.82 to 0.68, tirzepatide 15 mg vs

Both Ozempic and Zepbound can cost more than $1,000 per month

PlexusDx emphasizes biomarker-informed decision-making to ensure each wellness intervention aligns with individual metabolic priorities and provider guidance

Furthermore, all discussed reports evaluate only acute effects of the treatment, and evaluation of long-term effects of the GLP-1R stimulation on the alcohol intake has not yet been reported

However, semaglutide costs less ($199/month compounded vs $349/month for tirzepatide) and still provides excellent results