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Mitochondrial metabolism and KRASMAPK axis in CRC chemoresistance Although chemotherapeutic agents such as 5-FU, oxaliplatin, and irinotecan remain central to CRC treatment, the metabolic adaptability of tumor cells continues to undermine their long-term efficacy [23]

Zhang W, Li R, Lu D et al (2025) Phospholipids and peroxisomes in ferroptosis: the therapeutic target of acupuncture regulating vascular cognitive impairment and dementia

Side Effects: Gastrointestinal side effects, such as nausea, are common initially but can be managed by gradually adjusting the dosage

While preterm infants are born before completing this critical accretion phase, resulting in lower total body L-carnitine stores compared to term infants, their immediate postnatal peripheral blood concentrations may paradoxically be elevated

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