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Frank deficiency (below 145 pmol/L): I start aggressive supplementation, often intramuscular for post-RYGB patients, and I will want repletion confirmed on a follow-up blood test before I am comfortable proceeding with surgery

10.1016/j.physbeh.2011.07.027 [DOI] [PubMed] [Google Scholar] Montkowski A, Holsboer F (1997) Intact spatial learning and memory in transgenic mice with reduced BDNF

Common maintenance approaches include staying at the dose where you stabilized (often 1.0 to 1.7 mg), reducing by one dose level from your peak (e.g., from 2.4 mg to 1.7 mg), or finding the minimum dose that prevents weight regain while minimizing side effects

Antioxidant Function: GPx enzymes convert harmful substances like hydrogen peroxide into water and safe compounds

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