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Cardiometabolic outcome trials Prospective study of older adults (mean age 68 years) using liraglutide 3 mg once daily for 24 weeks found improved body composition with reductions in central fat mass, and preserved muscular performance [86, 87], explained by increased myogenesis in myoblasts [88], and the recruitment of skeletal muscle microvasculature [89]
Human germline mutations in glutarate metabolism highlight its fundamental biological role, with loss of function mutations in glutaryl-CoA dehydrogenase (GCDH) resulting in glutarate accumulation and glutaric aciduria type 1 (GA1)a rare autosomal disorder characterized by dystonia, developmental delay and often death in early childhood 10
longum BL21 on the gut-brain-ovary axis in polycystic ovary syndrome: insights into metabolic regulation, inflammation mitigation, and neuroprotection
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