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Some research suggests that adequate B12 levels may support cognitive function, particularly in older adults, though evidence does not currently show that supplementation prevents cognitive decline in people without deficiency

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The mechanism involves the inhibition of angiogenesis, protein-protein interactions, enzymes, proteins, signal transduction pathways, or gene expression [113120]

The Category 2 designation was not a finding that BPC-157 is dangerous per se, but rather that insufficient human safety data exists to justify its use in compounded medications without the oversight of the standard drug approval process