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Accepted June 6, 2017.) References Bilen, M.A., Subudhi, S.K., Gao, J., Tannir, N.M., Tu, S.M., & Sharma, P

Body-Composition Research The GH/IGF-1 axis is closely related to body composition, including lean tissue signaling, lipid metabolism, tissue remodeling, and age-related changes in the somatotropic axis. Research on GHRH analogs, including sermorelin-related compounds, has explored effects on GH pulses, IGF-1, and lean-to-fat ratio in older adults. These findings do not directly prove body-composition benefits for all forms of CJC-1295, but they support the broader rationale for studying GHRH analogs in this area

10.1007/s00125-012-2582-5

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D., Sherman, P