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Funding This work was supported by Business Finland grant #1498/31/2019, Sigrid Juselius Foundation and the Academy of Finland (for A.S.) Conflict of interest The NADMED redox profiling method is a subject of patent application WO 2022/008802 (Euro and Suomalainen-Wartiovaara, 2022, 2023a, 2023b

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The indirect effects, however, are real: Reduced caloric intake limits the raw materials available for muscle repair and growth