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After 28 days at room temperature, discard the opened pen or vial, even if medication remains inside
Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects (Sansgiry et al., 2017)
The dose is usually increased every 4 weeks until the maintenance dose is reached: Weeks 1 to 4: 0.25mg once weekly Weeks 5 to 8: 0.5mg once weekly Weeks 9 to 12: 1.0mg once weekly Weeks 13 to 16: 1.7mg once weekly Week 17 and onwards: 2.4mg once weekly (maintenance dose) Your treatment provider may adjust this schedule depending on how well you tolerate the medicine
Jhawer, M
HUBERMAN: It also can access the brain itself
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