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Synergy is inferred from the individual mechanisms, not demonstrated in combination: GHK-Cu: Cosmetically Focused Clinical Data Split-face human dermatology trials on wrinkle depth and skin density (n usually under 50 per arm) Microarray gene mapping (4,000+ genes)

If you are looking at B12 injections, the most useful starting point is the NHS treatment pathway, because it is built around how the body uses and stores B12 rather than around how often a top-up feels nice to have