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Male mice were randomly assigned to 21 days of vehicle or orforglipron (1 mg kg 1 ) injection and were retested with the opposite treatment after 10 days of rest

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Because of its role in metabolism, L-Carnitine is commonly incorporated into wellness, fitness, and weight management programs to support healthy energy levels and overall metabolic function

Studies examining women with PCOS treated with liraglutide have shown improvements in menstrual regularity alongside metabolic benefits, suggesting that GLP-1-based therapies may positively influence reproductive function in this population through insulin sensitization and weight loss

Additionally, Western blotting analyses confirmed that P-Mn/TI@mHSA preserved high levels of platelet activation markers CD62P, GP-VI, and GPIb on the surface (Fig