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Can be used as monotherapy or in combination with other diabetes medications including metformin, sulfonylureas, SGLT2 inhibitors, and insulin

This includes swelling of the face, lips, tongue or throat, difficulty breathing, wheezing, fast heartbeat or feeling faint

Figures 1B , 3 ) is not fully ameliorated by conventional subcutaneous insulin administration, most likely because subcutaneous administration of insulin cannot fully compensate for the normal portal delivery of insulin to the liver

The validation cohort included 189 participants: 76 healthy controls and 113 with carcinomas