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In line with this, overexpression of wildtype METLL16 enhanced the expression of CBS with 3UTR-1 mutation but not with 3UTR-2 or 3UTR-3 mutation, further confirming the importance of these two sites in controlling CBS expression (Fig

More recently, systemic or topical administration (eye drops) of GLP-1 and GLP-1R agonists has been reported to prevent electroretinogram abnormalities and neurodegeneration of the retina in rat and mouse models of diabetes [7, 10]

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Care by an interprofessional diabetes health-care team composed of a diabetes nurse educator, dietitian, obstetrician and endocrinologist/internist with expertise in diabetes, both prior to conception and during pregnancy, has been shown to minimize maternal and fetal risks in women with pre-existing type 1 and type 2 diabetes

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