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Each has a different mechanism, a different depth (epidermal, dermal or mixed), a different trigger and a fundamentally different treatment requirement

Patients with genetic markers favoring strong GLP-1 response sometimes tolerate faster dose increases and achieve weight loss at lower volumes

Pattern 2: Step down to a lower dose For some patients particularly those who reached goal at the maximum dose a lower maintenance dose preserves most of the appetite suppression while reducing cost, side effects, and the burden of long-term use at maximum dose