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The conversion of methionine to cystine: Experiments with radioactive sulfur

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It is postulated that the skin lightening effect by cysteamine is due to its inherent antioxidant properties. The antioxidant also inhibits the melanin synthesis by decreasing the formation of dopachrome (the immediate precursor of eumelanin) and increasing intracellular glutathione, which shifts the eumelanin to pheomelanin synthesis, as well as to chelating copper ions required in melanogenesis

Clinical evidence: in a cohort study involving 4,125 elderly individuals, higher cereal-derived RS intake (15 g/day) was associated with a 28% reduction in serum IL-6 levels and a 35% reduction in TNF- levels compared to low-RS intake ( 90%sufficient to meet 25% of daily protein requirements and support tryptophan (serotonin precursor) and tyrosine (dopamine precursor) supply (304)

Gobet, F