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Overall, the findings supported our hypothesis that SP could regulate oxidative stress and promote reprogramming of macrophages to an anti-inflammatory phenotype, which restricted inflammation in an RA-specific context and restored synovial homeostasis

Intriguingly, when compared to the placebo arm, subjects supplemented with L-carnitine tartrate reported less muscle damage and inflammation as evidenced by lower levels of serum creatine kinase and CRP, respectively

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Higher concentrations aren't necessarily better and may increase irritation risk without proportional benefits