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In contrast, international guidelines for T2DM have yet to recommend these technologies broadly, with CGM recommendations typically restricted to patients in special circumstances (e.g., pregnancy or those requiring insulin therapy with multiple-daily dosing regimens) [84-87]

Studies have shown that patients taking GLP-1 medications experience significant weight loss , which often includes a reduction in visceral fat, the type of fat stored around the abdomen and internal organs

Beyond the primary endpoint, the trial revealed a 22 percent reduction in a composite kidney endpoint, suggesting renal protective effects

The identity of the membrane receptor that mediates the latter effect remains to be conclusively established but our data suggest it is distinct from the GLP-1R