Patient education By presenting this case, we aimed to highlight that treatment with a SGLT-2 inhibitor increases the risk of DKA in situations of illness, decreased carbohydrate intake or reduced insulin doses
Jitschin R, Hofmann AD, Bruns H, Giessl A, Bricks J, Berger J, et al
After reaching your lowest weight, the goal shifts to maintaining results
Quantitative real-time polymerase chain reaction (PCR) analysis Total RNA was extracted using a TRIzol kit (Invitrogen, Carlsbad, CA, USA) and cDNA synthesis was performed using a cDNA synthesis kit (Fermentas Life Sciences) according to the manufacturer instructions
86,87,88,89 To prevent lactate accumulation from leading to lactic acidosis, pyruvate dehydrogenase (PDH) catalyzes the production of acetyl coenzyme A from pyruvate, which joins the TCA cycle and irreversibly removes lactate