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Hyperglucagonemia is associated with type 1 and type 2 diabetes, leading to increased hepatic glucose production and hyperglycemia 39,40,41

Treatment for B12 deficiency without neurological involvement: For patients with haematological manifestations only (macrocytic anaemia) or asymptomatic deficiency, the regimen is hydroxocobalamin 1mg intramuscularly three times weekly for two weeks (total of six injections), followed by maintenance of 1mg every three months for life

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While theres the promise, 5-Amino-1MQ research is in its infancy