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In the case of excessive ROS production, other redox-sensitive systems are affected, such as expression of endothelial nitric oxide synthase (eNOS) (4)

SOD This highly-effective, specific superoxide dismutase (SOD), is able to support neutralization of the most destructive free radicals in the body

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20 kg: 55 mL/m 2 (provides 5.5 g/m 2 of sodium phenylacetate and 5.5 g/m 2 of sodium benzoate) IV loading dose, then can follow with maintenance dose, as above

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