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Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1 Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage

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Although the data are mixed with some studies demonstrating no effect of supplemental vitamin D and/or Ca on bone health (76, 77) there are several well-controlled clinical trials and meta-analyses suggesting there is a synergistic relationship between intake of Ca and vitamins D and K on markers of bone health (i.e., bone mineral density, circulating levels of biomarkers associated with bone health, and risks of fractures) (4447, 78)