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Nature Medicine , 19(5), 576-585

Exendin-4 and liraglutide reduced the expression of genes involved in cholesterol synthesis and bile acid synthesis and increased the expression of genes involved in low-density lipoprotein cholesterol uptake and reverse cholesterol transport in palmitic acid (PA)-treated HepG2 cells

Another study reported BD patients (75 euthymic, 14 manic/hypomanic, 45 depressive) had higher levels of all cytokines, including slL-2R, C-reactive protein (CRP) and sTNFR1 than the healthy controls [73], with depressed BD patients having reduced sTNFRl and slL-2R compared to those in mania and euthymia [73]

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Growth Hormone (GH) secretagogues, on the other hand, work systemically by prompting the pituitary gland to release more of its own endogenous growth hormone